Collaborative Research Center 1333
Molecular Heterogeneous Catalysis
in Confined Geometries
Stereoselective oxidation catalysis in adaptive chiral confinement of dynamic metal-organic frameworks
We will control stereoselective oxidation reactions by catalysis in responsive confinement of Fe-based dynamic MOFs. Instead of chiral side groups we utilize homochiral BINOL-based linker backbones to generate chiral pore environment in a dynamic framework that structurally adapts to substrates and intermediates for improved stereoselectivity. We will explore the stereoselective oxidative phenol coupling of naphthols and acyclic tripeptides with product scopes relevant for arylomycin antibiotics.
Research focus in the second funding period (2022-2026): Regulation of molecular heterogeneous organocatalysis by dynamic confinement in soft porous crystals
Establishment and usage of flexible metal-organic frameworks (MOFs) as innovative catalysts able to responsively adapt their internal micro/mesoporous confinement by molecular recognition.
F. Neubauer, K. Endo, F. Bender, E. Ciftci, N. Hansen, S. Krause, B. Uekermann, J. Pleiss
J. Chem. Inf. Model. 2026, 66, 10, 5869–5879.
K. Gjorgjevikj, E. Çiftçi, D. Blaimer, T. Manitz, K. Leopold and S. Krause
ChemRxiv 2026.
W. Barakat, M. Benz, M. Dyballa, K. Endo, M. Nowakowski, M. Paetsch, H. Shatla, M. Singh, D. Strassheim, S. Krause, B. V Lotsch, M. Bauer, D. P. Estes
ChemRxiv 2026.
E. Çiftçi, B. Ortín-Rubio, S. Tokuda, F. Heck, F. Stemmler, K. Küster, S. Canossa, J. Van Slageren and S. Krause,
ChemRxiv 2026.
M. Kirchhof, S. Krause, L. Rautenbach, J. Wacker, A.-K. Beurer, H.-H. Nguyen, W. Frey, Y. Traa, D. P. Estes, A. Zens, S. Laschat
Adv. Synth. Catal. 2026, 368,e70213.
W. Barakat, F. Heck, M. Paetsch, H. Shatla, M. Dyballa, S. Krause, B. V. Lotsch, D. P. Estes
ChemRxiv 2025.
S. Kolin, M. Marquardt, G. Fläschner, S. Naumann, K. Pluhackova
ACS Materials Lett. 2025, 7, 3714–3723.
T. Manitz, F. Heck, S. Rezeki, K. Gjorgjevikj, S. Tokuda, S. Bette, S. Canossa, D. Leistenschneider and S. Krause
Small 2025, e06833.
J. E. Knapp, B. Ortín-Rubio, F. Heck, K. Gjorgjevikj, A. Sleptsova, S. Krause, S. Bette and B. V. Lotsch
Chem. Sci., 2025,16, 13646-13654.
Z. Dilruba, A. Dadgar Yeganeh, S. Kolin, S. Noor, H. Shatla, C. Wieland, B.-H. Yu, K. Gugeler, A. Zens, J. Kästner, D. Estes, K. Pluhackova, S. Krause, S. Laschat
Inorg. Chem. Front., 2025, Advance Article
L. Cusin, P. Cieciórski, S. Van Gele, F. Heck, S. Krause, P. W. Majewski, B. V. Lotsch, W. Danowski and P. Samorì
Nat. Synth 2025, 4, 632–641.
M. Kirchhof, D. Batman, E. Nicholas, W. Frey, V. Derdau, A. Zens and S. Laschat
Eur. J. Org. Chem. 2025, e202401270.
– PERSPECTIVE – K. Hemmer, H. L. B. Boström, S. Krause, B. V. Lotsch and R. A. Fischer
Commun Mater 2024, 5, 264.
M. Marshall, Z. Dilruba, A.-K. Beurer, K. Bieck, S. Emmerling, F. Markus, Ch. Vogler, F. Ziegler, M. Fuhrer, S. S. Y. Liu, S. R.Kousik, W. Frey, Y. Traa, J. R. Bruckner, B. Plietker, M. R. Buchmeiser, S. Ludwigs, S. Naumann, P. Atanasova, B. V. Lotsch, A. Zens and S. Laschat
Eur. J. Org. Chem. 2024, 27, e202400283.
– REVIEW – B.B. Rath, S. Krause and B. V. Lotsch
Adv. Funct. Mater.2023, 2309060.
– PERSPECTIVE – S. Krause and J. V. Milić
Commun. Chem. 2023, 6, 151.
J. Wachlmayr, G. Fläschner, K. Pluhackova, W. Sandtner, Ch. Siligan and A. Horner
Commun. Chem. 2023, 6, 135.
M. Kirchhof, K. Gugeler, A.-K. Beurer, F. R. Fischer, D. Batman, S. M. Bauch, S. Kolin, E. Nicholas, R. Schoch, Ch. Vogler, S. R. Kousik, A. Zens, B. Plietker, P. Atanasova, S. Naumann, M. Bauer, J. R. Bruckner, Y. Traa, J. Kästner and Sabine Laschat
Catal. Sci. Technol., 2023, 13, 3709-3724.
© University Stuttgart 2026
