B10 – Multi-site oxidation catalysis in MOCOFs
Aerobic oxidation catalysis by multi-confinement of metal ions in porous crystals
We aim at the selective aerobic oxidation of organic molecules using multi-confinement of metal ions in MOF–COF hybrid frameworks (MOCOFs). We will confine various metal ions (M1, M2) in MOCOF-1-(OH)2 to create laccase-mimic active sites: M1 mediates one-electron redox, M2 forms a trinuclear center for O2 reduction, and the covalent M1–M2 pathway ensures fast electron transfer. These catalysts with different metals and geometries will be tested for aerobic oxidative dimerization of alkenyl phenols under confinement, as well as C(sp3)–H oxidation using the M1 site as a confined HAT mediator.
