Project B02

Continuous-flow and on-line analytics

  • Project leader(s)
  • Team
Prof. Dr. Michael R. Buchmeiser
Prof. Dr. Michael R. Buchmeiser
University of Stuttgart
Prof. Dr. Ulrich Tallarek
Prof. Dr. Ulrich Tallarek
Philipps University of Marburg
Boshra Atwi
Boshra Atwi
University of Stuttgart
Jan-André Böth
Jan-André Böth
Philipps University of Marburg
Vincent Gramm
Vincent Gramm
University of Stuttgart
  • Summary
  • Publications

Continuous-flow microreactors and multidimensional on-line analytics for catalytic reaction kinetics studies under spatial confinement

We will study Mo-alkylidyne N-heterocyclic carbene (NHC) catalyzed, alkyne metathesis-based macrocyclization and (Z) selective Rh NHC-catalyzed hydrosilylation and hydroamination reactions of alkynes, all under confinement. The overarching idea in the use of these entirely different catalytic reactions is to develop a unifying concept for confinement effects in catalytic reactions with both large and small substrates. Reactions will be run in continuous-flow microreactors. An instrumental platform with on-line separation and detection will be established to quantify conversion and selectivity under the respective reaction conditions and to determine reaction kinetics rapidly and reproducibly.

Research focus in the 1st funding period (2018-2022):
Immobilized Molybdenum Imido, Tungsten Imido- and Tungsten Oxo Alkylidene N-Heterocyclic Carbene Complexes for Olefin Metathesis

Manipulate – techniques to manipulate the surroundings of a synthetic catalyst to control activity and selectivity: general discussion

Manipulate – techniques to manipulate the surroundings of a synthetic catalyst to control activity and selectivity: general discussion

 - GENERAL DISCUSSION - T. Beweries, M. R. Buchmeiser, N. R. Champness, M. Costas, A.  Duhme-Klair, J. Echeverría, O. Eisenstein, C. T. J. Ferguson, J. C. Goodall, R. Gramage-Doria, M. Gyton, R. Ham, S. Herres-Pawlis, Ch. L. Johnson, P. Kennepohl, B. Lewandowski, P. R. Linnebank, S. A. Macgregor, K. T. Mahmudov, E. Meeus, M. Navarro, P. Ntola, T. N. Parac-Vogt, R. N. Perutz, A. Poater, D. C. Powers, S. Pullen, P. R. Raithby, Joost N. H. Reek, T. R. Ward, A. S. Weller and H. Wennemers

         Faraday Discuss., 2023, 244, 96-118.

Make – underpinning concepts of the synthesis of systems where non-covalent interactions are important: general discussion

Make – underpinning concepts of the synthesis of systems where non-covalent interactions are important: general discussion

- GENERAL DISCUSSION - T. Beweries, M. R. Buchmeiser, F. E. Bugden, N. R. Champness, B. Chanbasha, M. Costas, J. Echeverria,   O. Eisenstein,   C. Ferguson,   J. C. Goodall, R. Gramage-Doria, M. Greenhalgh,   M. Gyton,   R. Ham,   P. Kennepohl,   B. Lewandowski,   W.-Ch. Liu,   S. A. Macgregor,   K. T. Mahmudov, E. Meeus,   J. Morris,   P. Ntola,   T. N. Parac-Vogt,   R. N. Perutz,   A. Poater, D. Powers,   P. R. Raithby, J. N. H. Reek,   I. Riddell,   T. R. Ward,   A. S. Weller  and  H. Wennemers

       Faraday Discuss., 2023, 244, 434-454.