4:00 pm – 5:30 pm
Lecture Hall 57.06
We are very happy to welcome within the CRC 1333 Colloquium Series:
Monday, June 26, 2023, 4:00 – 5:30 pm
Topic: “Mechanistic insights into electrocatalytic reactions from EPR spectroscopy”
Her research focuses on several themes, all of which are underpinned by the study of unpaired electrons. She and her research group use electron paramagnetic resonance (EPR) spectroscopy (in combination with other techniques) as a powerful method for obtaining detailed information on the structure, function, reactivity and environment of these ubiquitous spin centres.
During this CRC 1333 Colloquium Series, the CRC 1333 Master Prize 2022 will be awarded.
The CRC cordially invites all who are interested to the lecture.
Unpaired electrons play an important role in a wide range of redox-driven catalytic processes in both chemistry 1 and biology 2. Controlling their location and exploiting the interactions with their environment can provide key mechanistic information into these catalytic reactions. In this talk I will discuss how we have used and developed EPR-based techniques to gain mechanistic insights into electrocatalysis.
I will introduce film-electrochemical EPR spectroscopy (FE-EPR) and show that it is a powerful tool to investigate surface-bound molecular catalysts, which are increasingly of interest in sustainable chemistry. With FE-EPR we have direct and accurate control over the redox state, even of ‘buried’ redox centres in proteins.3 We can further monitor the evolution of radicals during redox reactions, including catalysis, in real time under flow conditions, at room temperature and in aqueous solution.4 Such in situ and operando FE-EPR provides detailed insight into the mechanism of nitroxide-catalysed alcohol oxidation. FE-EPR gives access to substrate binding affinities, catalytic rate constants and reduction potentials during catalysis, and provides a new means of benchmarking electrocatalysts and their reactions. Lastly, I will provide an outlook for the application of FE-EPR to biocatalytic reactions.
1 M. M. Roessler and E. Salvadori, Chem Soc Rev, 2018, 47, 2534–2553.
2 K. H. Richardson, M. Seif-Eddine, A. Sills and M. M. Roessler, Methods Enzymol, 2022, 666, 233–296.
3 K. Abdiaziz, E. Salvadori, K. P. Sokol, E. Reisner and M. M. Roessler, Chemical Communications, 2019, 55, 8840–8843.
4 M. Seif-Eddine, K. Abdiaziz, S. Cobb, M. Bajada, E. Reisner and M. M. Roessler, under review.